This topic kinda belongs on the ISBoxer.com forums since it's strictly ISBoxer tech support.

Here is the 64-bit support announcement: http://isboxer.com/forum/viewtopic.php?f=22&t=5450

If you want to revert to the previous build, just go into the Inner Space Patcher window and un-tick the devleopment build option, and re-launch Inner Space to let it patch up. However, it would be more beneficial in the long run (e.g. after this build goes live) for us to figure out why this is happening for you

So it might help to see your ISBoxer configuration. http://isboxer.com/wiki/Configuration_Sharing It would also help to know what your in-game video settings are, particularly the windowed mode setting, and whether you're under DirectX 9 or DirectX 11.

I also just noticed that I have no is1 window.
That is interesting. I also want output from the main Inner Space Console in this case. Right click Inner Space and select Console, and in this console enter the command "sessions" -- this will list all of the processes Inner Space is managing.