Your question is a bit too vague to be able to begin answering terribly usefully. Are you looking for software advice, macros, tactics, or what? If you are looking for that stuff, check out the getting started, software, and macro boards.

If you're looking for more conceptual suggestions, the way I have always handled a tank + ranged combo is to drive from the ranged character and treat the tank like a Warlock or Hunter pet. Put the tank on click to move, have all their abilities also perform interact with target, and go from there.

If none of that is what you're looking for, be more descriptive of what you want.