It does take a little getting used to, but no more than anything else you'll have to understand to start boxing - it's not that hard, and you can use as much or as little of it as makes sense to your use-case. I haven't started on Jamba macros yet for example, even though they sound awesome, simply because I don't have the need for them with what I'm doing so far.
It's primarily a boxing tool, but I find myself using the quest-item bar even when playing solo.
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