Yes, there's a DISPLAY# drop down in the maximizer tool.

What version of windows are you running? XP seems to have no problems when running span mode across monitors but goes to crap when running dual-view. Vista was supposed to be problem free when using dual-view but does not have span-mode (thanks Microsoft! ). I'm having some performance degradation using Vista and dual-view but the PiP worked fine when I tried it across two monitors.