concerned that with a 27" main monitor that it's going to require lots of head movement and I'll end up with a sore neck in about a week.
I use 2x 30" 2560x1600 monitors and don't have any problems like that. As long as they're not too close to you it should be fine.



Have you looked at the mouse repeater + addon method?
http://www.dual-boxing.com/threads/3...albot+repeater