One of my teams consists of 2 DK's and a Holy Pally. I found that on my pally i didn't have enough buttons to heal as precisely as i would normally. So now i use my Naga (or G600) to control my Pally only and i use my G13 to control the two DKs. So i use Numpad and Shift Mod numpad on my pally and i use normal numbers and ctrl normal numbers on my DK's. This means no overlap with keybinds that might cause errors in heated gameplay or poorly structured macros/software setup. I also have enough buttons to keybind all of each toons abilitys so i can use the exact right ability for the situation.

This sounds like an overly complicated situation that ends in tears.