Starting out with HotKeyNet

[Khatovar]

Yup. If you have Partial Match enabled under Options > Settings > Window Name Match you can make use of an IF statement

<Hotkey CapsLockOff MyList; CapsLockoff Shift MyList; CapsLockOff Alt MyList; CapsLockOff Ctrl MyList; CapsLockOff Ctrl Alt MyList; CapsLockOff Shift Ctrl MyList; CapsLockOff Shift Alt MyList>
	<If ActiveWinIs WoW>
	  	 <SendLabel w1, w2, w3, w4, w5>
   	<Key %Trigger%>
		<Else>
			<SendPC Local>
		<TurnHotkeysOff>

Using If ActiveWinIs WoW means that if you are in any window starting with WoW then your keys will act normally. If you aren't, as soon as you use a key in that list, it will pause HotKeyNet.