Quote Originally Posted by Apatheist View Post
The advantage of doing it this way is that it opens an entire set of keybinds for every mouse button you have available. I use a Naga mouse with mod keys on buttons 1 through 6. Meaning all the easy to access keys (1-6, F1-F4, Q-R, A-F, Z-V, space, tab, tilde) all have 6 functions each depending which mouse button I use them with. I don't even use the rest of my keyboard anymore and I never need to take my hand off the comfortable WSAD pad.

It takes a bit of getting used to, but once you get to the point where you're familiar enough not to have to think about it, it increases your reaction time quite a lot. Also removes the necessity for awkward keystrokes (SHIFT+Alt+X, etc).

The disadvantage seems to be if you derp the modifier release before the movement key release, your toons will continue to move in the direction they were going.

Maybe this is my razer mouse + G510 issue, but its there.

If I use alt instead of mouse 4 they don't do it. So I can only surmise this is because of a hardware conflict.