Pointing Inner Space at the 64-bit WoW client will not work. It would require monumental effort to have Inner Space support a 64-bit game client (probably similar reasoning to why it took them so many years to bother with a 64-bit client). To do this, I would need to separately provide 64-bit versions of each of Inner Space's DLLs, and each of them is highly specialized. Here is the related discussion on isboxer.com, complete with some giant asshole demanding I get 64-bit working immediately or he's not paying me another dime: http://isboxer.com/forum/viewtopic.php?f=2&t=1979

In short, I am unlikely to spend the required amount of time rewriting most of Inner Space 1 to support 64-bit game clients (just for WoW, mind you), especially without a price increase (though keep in mind prices have been the same since I started Lavish in 2004).

Inner Space 2 and Joe Multiboxer (ISBoxer's replacement) on the other hand, are much closer (code-wise) to supporting 64-bit game clients, and it's already a rewrite of Inner Space 1. I do not have a solid ETA for you. These things have been pushed back by important ISBoxer development (which I am sure most will agree has been beneficial), along with real life. Adding the 64-bit requirement for IS2 will push it back even further as well.