one of the biggest differences i see in the boards is the number of PCI-E lanes. If you think you might want to do SLI go with the asus or any other Z68 board. if your just going to run a single gfx card any p67 board will do, the gigabyte board mirai is reccomending is an awesome board, i have several boxer friends that use it. i know the p67 boards say they support SLI but when u actually use both slots they downclock to 8x if you want true 16x 16x sli you will need a z68 board. thats just my opinion