I couldn't wait and decided to 4-box this after playing a solo toon to 29. I couldn't more strongly recommend the game to a person that enjoys MMOs. It's amazing. The storylines are engrossing and the voice acting is amazing.

Multiboxing? Wait until they fix follow. I read all the feedback about how follow was broken and I... underestimated how bad it really is On the main screen you'll see all of your alts following you. The alt screens will have some of them stuck on stuff, some just randomly stopped and rarely they'll actually be where you see them on the main screen.

This is just a follow issue that I've seen. The lag in-game is, for me, much more negligible than in WoW. It's just that follow is bugged currently.

So, single box until they fix follow: Yes.
Multibox now: No.