I'm using a naga mouse with ISboxer, even though not boxing right now. I built myself click casting ability, it just kills my hands to be a healer without that. Never seen a game yet that won't allow mouse button programming style macros for this reason.
BTW if I was boxing I imagine the click casting would work smoothly with the click through frames to get around some of the lack of macros. Thats how I used to have healers, cures, etc, set up in wow.
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