I have my Paladin set to heal her Focus, when I spam my "1", "2" or "7" keys.
Which I believe are my DK's three attack spam keys.
If she has no Focus, then those keys do nothing on the Paladin toon.
Essentially, she alternates between "1" and "2" as her output, when I press either of those three keys.
I also have mouse scroll wheel up, set in Clique, as Focus this frame.
So while spamming my DPS sequence, the Paladin either frantically uses her maximum healing output macros or she doesn't cast anything.
I can use the Grid mouse-over healing, if I want to spot heal anyone in the party.
Or for that matter anyone in the BG or raid, as the Grid will display up to a 40-man.
I'm not sure if this is exactly what you're looking for.
It is probably not quite.
Essentially, if I have a Focus set then it heals via buttons rather than precise control over healing via the Grid frame.
And it does use Focus as the targeting method.
http://www.dual-boxing.com/showthread.php?t=37658
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