You could likely do this software side.

Have a keybind that changes you from one stance to another.
I know Presence =/ Stance, but "Mode" is as good a word as either here.

You could also do this with the default UI, and the /changeactionbar function.

Set it so when you press "x" (whatever your runic power dump keybind is), the game receives "y" when in Presence A or "z" when in Presence B.
With the actionbar changing, you'd have Rune Strike on say "3" and Death Coil also on "3".
But have the macro for Stances/Presences... change to the relevant Actionbar when one is chosen.

Software side, you'd have (using IS Boxer terminology here) a toggle set up.
Two mapped keys, with the same keybind to activate them.
When you send "Keybind for Stance/Presence A", it also activates Mapped Key A and deactivates Mapped Key B.
So whenever you're in Presence A, your "3" key (hotkey) will output Rune Strike.
But when you're in Presence B, your "3" key will instead output Death Coil.

Either way, you have the same hotkey for the runic power dump.
While the game cannot tell what your stance/presence is, your previous action (choosing the Presence) can set up your hotkey to be the "correct" runic power dump.

Hope this helps some.