If you have a profile saved per account...

You could also enable mouse broadcasting.
And configure, or click the already selected option, on one toon.
So the other toons (each on their own account) now have the same option.

At which point, you have one toon on each account with the options configured exactly as you want them.
Then do a profile copy to the other toons on each account, from the one toon that is configured.