So far running around Org I haven't been able to replicate the issue running as Admin. Pass mouse clicks isn't checked.

So now to the issue having w/ it as admin:

I can't use any mouse buttons I have assigned to keystrokes, in this case CTRL + Numpad 1-4

Nothing happens when I press the mouse buttons, which are currently bound to stances, attack, and ranged attack. Pressing the actually CTRL+NUM1 works. And all other mouse buttons work (1-5)

edit:
Playing with the mouse map, the box for mouse input will recognize buttons 1-5 but not the ones bound to keystrokes.

Edit:
Got it to work, running the mouse software as admin, then reseting up the buttons.