D3 looks very similiar control-wise to D2 - some use of keyboards for actions, major use of mouse for movement.

It's nigh (love that word) impossible to multibox D2. In fact, it is quite frustrating controlling two characters in that game. I play D2 off and on and whenever I have to rush my characters thru levels, it is a PITA constantly mousing over to click and move them somewhere.

I believe D3 will not be possible to multibox. But I will still have two accounts so I can rush characters, and for any other unknown benefits.