I dont have any experience using octopus for LOTRO but I can make a suggestion and say try Hotkeynet I have had no problems setting it up for LOTRO and there are a few sample as well as a full LOTRO script posted in the forums
A good option, unless you want to use the KM feature of Octopus on multiple PCs. In my experience, Octopus did not play well with Synergy/Input Director.
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