Here is my prot warrior setup, 4 macros that are spammed at the press of one button:

Macro 1:
/startattack
/cast Shield Block
/cast Shield Slam

Macro 2:
/castsequence reset=target Rend, Devastate,Devastate,Devastate
/cast Heroic Strike

Macro 3:
/cast Revenge

Macro 4:
/cast Victory Rush

This is for single target, aoe tanking button replaces macro 2 with this macro:

Macro 2:
/castsequence reset=target Rend, Devastate,Devastate,Devastate
/cast Cleave

Thunderclap and shockwave are separate buttons that I press individually.