I think the OP was wondering how much RAM is sufficient for boxing 5 clients as opposed to boxing 5 clients plus doing extra shit.
It was only recently that the amount of RAM a client was allowed to use was increased from 1.2GB to 2GB so 8GB has been fine for a while and will continue to be as long as you are not running a lot of crap in the background/addons etc. My 12GB is only ever 6-7GB full running a few addons like Jamba, Isboxer, Gladius, Auctionator.
I assume swiching to a 64bit client will increase memory requirements slightly and given the price of memory now, I would agree with the recommendations above of going for 12-16GB if you are planning a new build.
The memory speed is only really important if you are planning on overclocking. Saying that, I have no experience with the sandy bridge procs so it may not be necesary in this case.
If you have the system and can test it, get yourself 4 trial accounts and log the all into stormwind/org and see how you go.
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