*shrug* I'm in the same boat as Fenril. I enabled certain addons by default based on the ingame character selection and used Addon Control Panel to create and swap addon sets when I needed to "fine tune" what addons I was using based on what I was doing, such as killing Gathermate, TomQuest and SilverDragon when I was just going to dungeon hop in the LFG, or turning off things like DBM, Omen and Recount if I was going to be questing.