In the Upper box in ISboxer there is a section called Action Target Group you can make a target group for each one of your classes then you can make a new mapped key for a rotation that sends just to the specific action target group, then you can have your mapped keys 1-= do a new mapped key action and call on the mapped key for the action target group.

the way i handle healing is i mark everyone up in the group 1-5 with a raid mark. Then my cleric has a macro
#show Healing Spray
cast @mark 1 Healing Spray

and he has a macro

#show Restorative Flame
cast Caregiver's Blessing
cast @mark 1 ward of the ancestors
cast @mark 1 Restorative Flame

So i make an action target group called Heals
then in non combat i make a new mapped key called Heals
Then it has 2 steps first one is do new key stroke action target group all of heals keystroke combination is 1 at the top i have do not advance to next step for 1.5 seconds

step 2 is do new keystroke action target group all of heals keystroke combination is 2 at the top ihave do not advance to next step for 12 seconds. because the hot doesnt need to be refreshed for 12 seconds.

then in combat on my keymap for 1 it says domapped key non combat assist-> all others
then 1->tank
then do mapped key non combat heals-group all of heals