Probably something minor but when ever I kick on Inner Space and launch my games my click to move turns off on all of my accounts. I am thinking this is probably a keybind conflict or something. Any suggestions?
The Quick Setup Wizard generates CTM On and Off macros in the game on Shift+Alt+N (on) and Ctrl+Alt+M (off). These are used by the standardized "Interact with Target" Mapped Key in the "General" Key Map, in order to temporarily enable CTM (on "all other" windows) for the IWT, and then turn it back off (on "all" windows).

If you prefer to keep CTM enabled permanently, you can replace the IWT mapped key with one that just sends the IWT keystroke instead of messing with CTM. Or you can just go into the Step 2 for the existing one, and remove the Action that disables CTM (leave the empty step unless you also change the Mapped Key to "pressed" or "released" instead of "pressed OR released")

If your issue is NOT from using the base IWT, but instead from trying to use Ctrl+Alt+M, the CTM Off macro (and key binding) is assigned through the Game Helpers, World of Warcraft section under Quick Setup 38, called "Click-to-Move OFF". You can remove the Hotkey by changing it to a blank, and then it will be impossible to activate this macro by any method other than /click CTMOff. Or alternatively if your Quick Setup maps are from ISBoxer 37 or earlier, the actual macro is defined in the Click to Move Off mapped key in the Control key map.

That should sufficiently answer your question.

Also, Chubbz is spot on with running Vent as Admin for the PTT key.