in theory, yes. setting it up would be a pain

keyclone/setup/maximizer
reset
hit '+'
adjust for full screen
set name properly

hit '+' again
adjust for full screen using the edit fields at the top (avoids potentially clicking background region)

repeat for all your regions
--

then in keyclone/setup/command editor
set maxfps to 40+
set the maxfpsbk to 5.. you won't see them, so drop it real low until you bring to the foreground

let me know how that goes.