I don't let my main die. 8)

Since I'm a PVEer -- running pally, priest, magex3 -- when my tank falls that's usually a wipe. When it happens I try to keep calm, bubble up, go all out with the mages and try to keep the priest up. If I'm lucky the battle was almost over and then I can rez.

PS: you can continue to target with the main after they are dead.