Danji,
Regarding accidentally firing off 2 Death Grips:
If you use ISBoxer, set up your DG hotkey with 1 step for each DK, each with a Delay Before Advancing To Next Step of ~1.3s.
You can Spam this key a few times, in case the char who's turn it is is in the middle of a GCD, and it will 'wait' on that char's turn for 1.3 sec, giving them time to get their DG off.
Set the overall delay of the entire Hotkey to the CD of Death Grip, and it will reset back to the first chars DG after the Cooldown is up.
Hope this makes sense.
**EDIT - As for the Latency thing, that's exactly right. You will get used to waiting a fraction of a second after retargetting in WoW.
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