I played pally tank, holy/disc cleric, destro lock, arcane mage, elem shaman from 15-60 only doing instances using my instant LFD queue. I had previously played pally tank and 4 enhancement shamans, only switching to 1 resto/3 elem in the 80s.

The mixed team started out really slow. At the beginning I couldn't do enough damage with a full power pool to kill some bosses (Oggleflint in Ragefire comes to mind). However, it just keeps getting better and better. After the early struggles, I did most of the 1-67 (team is currently at 67) content earlier and easier on the mixed team. I wouldn't have attempted it without using Mercurio's two-step macro idea and it takes some work to refine those as you level but is definitely satisfying when you have it all set up. I'm not sure I could go back to a less diverse team now.

Other than that, I'd second the advice to use a pally tank. While it might be easy mode if you are playing 1 character, there is plenty to do playing 5.

Alge