I imagine the issue you're having is that it looks pixellated. Unfortunately the actual pixels that you see on the screen if the window is visible, in the small window, is exactly what is going in the video feed. The bigger the "slave" windows, the better your feed is going to look.

You don't actually need a window layout, you can just leave them full size behind the main window. That way, you can just pop a few video feeds on whichever window is your main, and any feeds will be full quality since the source window isn't scaled down.