I've been experiencing this quite a bit - but it's mainly affecting my casting. Noticed it during peak hours (6pm - midnight, local). Turns out by running WinMTR we were able to trace it to a single hop on AT&T's network. I've contacted them to hopefully get it straightened out.
http://sourceforge.net/projects/winmtr/
That's where you can get the WinMTR program. Point it at the IP for your server, which can be found :
http://www.wowwiki.com/US_realm_list_by_datacenter
And let it rip. Might be a source of problems for you, might not.
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