1, Not if you're using ISBoxer, as Ugh said - ISboxer sets up virtual configs for each session of WoW - works really well.
2. Nope, in fact the current beta of ISboxer has built in support for DX11 - I get a few more FPS running it in DX11 mode compared to DX9.
3. Nope, I'm running it under Win 7 Pro 64-bit and it's fine.
4. MS finally got their shit together for Win 7 - although arguably not much under the hood was changed from Vista, the final product was far more polished. Moving up from XP isn't a huge change as far as the user interface goes, some things have moved, but overall it should feel familiar. There are no issues for running WoW under Win 7 as far as I know...
Cheers,
S.
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