After tweaking my equipment a bit more, think I was going a bit too far on the hit with my previous reforging on my casters, I got my dps closer to the numbers Janus said I should expect. Not quite there yet, even with about iLvl 300+ on all toons. Also made a tank heal macro that gets spammed with my regular dps macros. Also switched to seal of insight on my pally which also helped a bit.

Progress so far is that I now actually make it to the first Stonecore boss, but I can't seem to take him down, keep dying everything he goes underground, but that is probably my own damn fault as I don't seem to be able to gather all the spawning spiders to my tank. Blackrock caverns went a bit better, got the first boss, but struggled with second, but with some practice I'll get her too.

Think I need to invest in a mouse with a few more buttons, that would probably also alleviate some of the healing problems I have with repeater regions.

Thanks for all the advice so far!