My only real suggestion is to refrain from overcomplicating things. Apply the Keep It Simple, Stupid rule to everything you do and add more complex features once you get the basics working. There's a ton of into on this topic in other threads but with a 5-class/spec group like this, there's really no way to tell you how to play. You'll have to figure out what works best for your A) play style, B) keyboard/controls/addons layout and C) intended objectives through experimentation.