The IWT/CTM circling (SPAMMING IWT), is beneficial in pvp... in pve, selective pressing (not spamming) is probably better.

It confuses the opposition more than static dps from one side.
And lets you stay with them, as they move; especially if you're faster and/or they're slower via debuffs etc.
When you're behind, they don't dodge/parry/block, which is a tradeoff from not always being on target.

You have to deal with your toons running off, no fix for that as it is how game pathing works.
You can re-send IWT, either the same target or another.
Or quickly issue a Follow command.

Occasionally your camera will uncontrollably circle about.
Fix this by right clicking anywhere on the ground, to "orient" your position.



Not sure that Keyclone supports alternating keys.
Where one thing is sent on press 1, and another on press 2.
Which some addons or software can change to Press = Action A, and Release = Action B.

I would probably change your bindings to something like 1 & 2 (DPS & IWT).
IWT is not on the Global Cool Down, so a penny across the keys so both are mashed together would work quite well... I'd just mash both keys, and not glue anything to the keyboard =p.