Two repeater regions cover my party frames. If I click the left, my holy pally heals (Left Click = insta heal, Shift Left Click = long heal, Right Click = flash heal) and in "Oh Sh!t" moments, if I click the right region, my druid heals. Just make the regions cover your whole frame instead of multiple little frames for each party member. The center of the frames are open so my DK can do the usual menu items.