Considering we've been running wow fine on older hardware (9800/8800) for a while now...
Herp derp. To my knowledge WoW does not utilize Physx, nor should it. It is correct that you can run non-matched nvidia cards so that one does physx and the other one does the rendering. THIS ONLY IMPROVES PERFORMANCE IF YOU WERE EXPERIENCING A BOTTLENECK IN THE FIRSTPLACE, AND ONLY IF YOU NEED PHYSX.
Again, to my knowledge wow does not use physx, so such a setup is pointless (for two characters. I fully support multiple cards when boxing 5+ characters for more performance, in which case rendering is split between cards)
The second card does NOTHING except for consume power and produce heat (albeit at lower levels than your main card)
I'm not sure what to say about that. Possibly a driver issue. Having run five clients across multiple monitors with both older nvidia hardware (9600GT/9800GX2) and newer ATI hardware (5850), I have had few issues.
TL;DR
YOU SHOULD BE JUST FINE WITH BOTH MONITORS PLUGGED INTO THE SAME CARD
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