Most of the macros in this thread are dependent on having two macros, and alternating between them.

Quite frequently, one will reach a point where it locks up.
You might not have Rage/Energy/Runic Power.
You might not have a Rune available.
Etc...

But by having two macros together, and alternating between them.
Even if you reach a point where the first locks for whatever reason.
The second should be able to fire (or if the second locks the first can fire).
One of them doesn't have anything that can stick or get locked up.
So by executing both, you hit all the stuff that you want.

And if one gets stuck, since you're spamming 1-2-1-2-1-2....
You won't sit there doing nothing, when "1" is stuck at some point in its sequence.