I know right now on my melee team my spam buttons have my priest doing nothing (i control his healing through vuhdo and repeater regions) but if i hold control then the priest joins in DPSing... something like that would work very well in theory, but imagine having 5 combinations of modifier keys to hold down to cast for different chars, yikes.

Ive been wondering if instead of mashing 444444444 or 555555 like im used to with my faceroll macros, if I could just setup 4 as dps key for char 1, 5 for char 2, 6 for char 3 etc and then instead of hitting 44444 im hitting 456456456456 , which would allow me to break out any of the chars for cooldown abilities or procs without affecting the others...

Not really sure yet. Waiting for 4.0 to start testing it.