I have extensive experience. I six boxed a group to 50 before I got tired of some of sonys stuff and canceled.

Regardless... I never had the issue your talking about. It either worked or didnt. After I got Innerspace my issues resolved.

Make sure that the second client has the buttons your pushing... for instance if k is aoe nuke on your main client, you would need to make k your aoe nuke on your alt clients.

I used 1 - 0 as my main tune. ins home pg up pg down end and del for my heals (fury and templar) and num pad 1 - 7 for my dps casters. Take a gander at your macros... other than that Im not sure why its not working.

Open up a note pad on both computers manually add it, and see if the keys your having issues with work.