In the beginning, I really had hard time to adjust myself to use this "light-weight" mouse (Note: yes, very light, and I feel the cable comes with it is heavier than the mouse): the biggest problem for me is that the mouse is over sensitive in a bad way - if i click on right/left mouse button, the cursor will move...ya it sucks. Sometime, even I don't touch the mouse, the cursor moves too because the mouse slightly moves on my "unnoticeable unbalanced desk". Pretty hard for me to get used to it, but I've managed to get used to it after-all. Ya,..a lot of wrist practices and steady hand exercises.
Beside that problem, I absolutely love this mouse. Especially, after I mastered to control all my slaves' movement with the side buttons, I can't live without it in my boxing life.