It's POSSIBLE that Diablo 2 will work with Inner Space as long as it's in Direct3D mode, which would allow you to force it into a window and potentially adjust it how you like. I haven't personally tested it and I have no idea where my Diablo 2 disc is to test it myself, so I don't know for sure

Definitely not Diablo 1 or Starcraft, which both use display systems not supported by Inner Space.

Future Blizzard games, on the other hand, should work fine. Diablo 3, SC2, etc.