Grats as the Gundrak kill.

You will find that as your group gear improves you will require less and less of the CC and special abilities. Keeping things efficient and simple will help greatly. I couldn't see the repeater regions in the screenshot but you can use several small regions over your VuhDo to controll more than one character's specials and you can remove some of your buttons. This will reduce your mouse movement. Just make a table of what each characters spells/macros are on a piece of paper until you have it memorized.

Good luck and have fun.