Not entirely sure what you mean, and only did (quite a while ago) a brief test with keyclone. What i did was fire up the wow clients one by one, then run keyclone in wine, and basically everything worked out of the box. I don't really saw a need to start wow from inside keyclone, unless u want to do PiP.
That being said i see little to no use for using keyclone under linux, since hotkeynet, autohotkey (compile exe, then run) and even isboxer are supposed to work with wine. Not to mention that there are some native linux tools that can accomplish the same.
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