Against the rules?

[Lax]

However, with ISBoxer, you no longer have to think about anything. You can just spam the 3 key as much as you want, and ISBoxer will take care of when the 3 translates into 1 and when the 3 translates into 2 using a clock. If it didn't use a clock then I'd have no issue with it... but isn't that all delays are is disabling something until a predefined amount of time expires?

What? This is not what a delay is in the context that Blizzard is concerned about. If a "delay" means you push a button for a while and different things might happen each time, then what do you think of /castsequence + /click? It's the same concept.

A delay in the sense that is considered automation is as follows: I press a key. 2 seconds later with no further action, as a result only of my pressing the key 2 seconds prior, something else happens. And hey, why stop there, 2 seconds later it happens again. And then again 2 seconds later. Now, 6 seconds apart, 3 things happened without my touching the keys, and I didn't even need to be at the computer anymore (this specifically is where "1 Key = 1 Action" comes from). ISBoxer does not provide any method of creating a delay.

If you are pressing the buttons to cause instant action at the time of the press (and/or release), and this action happens without any input from the game environment etc, and without otherwise breaking the EULA/ToS, you're not botting.

Past that if you think something you could possibly do might be against the rules, don't do it. From my understanding of the actual rules, and conversations between me and Blizzard, I don't see anything implemented in or configured through ISBoxer as being a problem. In the end everyone has different ideas of what automation means (especially who have no experience with bots) and so there's a lot of different interpretations of the rules, GM posts, etc. Use your own judgment and you'll be fine.

Edit:

I thought it would be able to push one button, and have ISBoxer go through different steps for the next 5 minutes if you set it up to do so.

Oh definitely not, thanks for clearing that up for us