I rarely got to Hadronox on heroic on my pallies. They still had the crappy crafted epic 2h mace (forgot the name) and were doing terrible DPS, so I always wiped on the guantlet because i couldn't kill the last wave fast enough before the boss aggroed. I did manage to get past the guantlet once on heroic, but got my ass handed to me on the last boss (can't remember why though...). When I enountered hadronox on heroic I simply used the same exact procedures as normal (you did kill her on normal right? if not, try practicing on normal).
As for hadronox I remember she was very easy in normal after some practice. Did you try grouping your paladins up? When she does the spew thing just mash your cleanse keys until your paladins are clean. If you have a /click set up on all your pallies then all you have to do is watch the ground for the poison cloud. When it appears simply strafe all your paladins to the right or left. They will move as one so it's much easier.
If you're getting runaways, do not mash the IWT bind. It is very consistent and you should never have to mash it, just hit it once to start attacking. Unlike /assist, where I find I have to mash that multiple times for everyone to get their targets. Also, make sure you aren't getting the classic runaways. That is where you release the shift key before the movement key. This happens if you are rushing things or are in a frantic movement situation.
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