Sorry to hear you're having trouble. Let's try to simplify the problem to help us figure out the cause. These three lines work on my PC:

[code:1]
<hotkey 1>
<sendpc local>
1[/code:1]

Could you try simplifying the hotkey definition to the three lines shown here, and see if the WSASend error pops up at the precise moment when you trigger this hotkey?

> Can I only make this work when I insert a named window?

You can define hotkeys without specifying a "send to" window. If you do that, output goes to whichever window has the focus (i.e. is active).

> And I cannot use the keys outside the running wow instance?

Sorry, I don't understand this question.

> Can I bind a key to temporarily shutdown the keysending?

No, but you can do that with the check box at the bottom of HotkeyNet's main panel.