I have 4xShamans on my 19" which is on the LHS due to my desk setup, and my mainscreen is 21" wide which is my druid. This is a bit of an old screenie my gear and the area im in is a little updated but i had this lieing around.

On my druid window, i have focus setup and totems and also the portrait of the focus near the minimap, all the focuskeys, totems are hotkeyed but there out of the road there. I was often forgetting my focus so i setup a little box there. There is also castbars on the party frame so i know if ive lost follow on someone if i havnt looked on that screen for a littlewhile.

Im pretty pleased with my layout at the moment, i have to reconfigure WindowSizer app so i can see my castbars rather than my taskbar on my bottom to windows however

Imageshack doesnt have 100% size, so heres a link for it: http://users.on.net/~opt/worldofoptcraft.jpg

Mods:
XPearl Unit Frames
Bongos Bar Mod
TwoInOneToolbox
Allinone Bag