At this point I almost find it difficult to work w/o 4 monitors. Love the real estate.
You can definitely still use the PiP swap but because you'd be swapping from a monitor using the secondary GPU to a monitor using the primary GPU you get the performance hit. Again, I'd love to test this on a motherboard with two x16 slots. But, I have a feeling I'll be buying a 30" for my main screen soon enough and I can just jam all 5 instances onto that main screen nice and easily.
i'm with you there man, i run a 3 screen setup at home(also running synergy with 3 pc's but could run them all on 1) and have a 5 screen setup here at work....i think the 5 setup is a little over kill...hold that thought STUPID PHONE CALLS... as they are lined up instead of stacked.makes it a royal pain in the ass to go from my "play screen" on the far left over 3 to my main work screen on the far right. think i need to do some convincing to le me do some "modding" on the supervisor desk :P
anyway, it IS possible to run mutiple instances of WoW on a single computer, you will take a hit in performance, the severity of the hit depends on how you set everything up, your hardware,software and instances. from my limited experience in the matter, SLI isn't good for multiboxing but it's definately better to run multiple cards if your using multiple screens.
*side note* HOW the hell do i turn off this stupid beeper?...and WHO USES BEEPERS ANYMORE?
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