One problem I ran into with ISboxer which is really not a problem with the software is the region layout. If you want the mouse repeater to be accurate on your alts all regions need to be the same aspect ratio. In order to do this I had to switch to boxing on 1 pc and using 2 monitors instead of 2pc and 3 monitors like I had with keyclone. Its a small sacrifice but the software is by far better than keyclone. It goes a step beyond keyclone. Once you heal your group with the mouse repeater regions you will wonder how you did it without it.