Mogulus just released a new program called procaster that practically makes it idiot proof and the quality is great . . . http://www.procaster.com/

Here is the channel I run, only have my guilds 25 man Ulduar Raid for the last few days so far. Once I upgrade my setup to i7 I will start streaming my multiboxing (running 5 client on one pc + broadcasting can be a bit laggy so i need the upgrade).

http://www.mogulus.com/NitroKoS