The nice thing about "click"...

You can easily drag a macro (castsequence) out of the click area.
And leave it as a blank button.

It is pretty easy to switch the order of spells.
Or omit spells entirely.

I like to have unrelenting storms, at least until my gear is at a point where mana regeneration is not an issue.
PvE gear seems to have so much mp5.
Maybe mix the gear a bit.
Experimentation is good.